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Cancer detection probe combining Raman and resonance sensor technology: experimental study on temperature dependence and effects of molding
Luleå tekniska universitet, Institutionen för system- och rymdteknik, Signaler och system.
2009 (engelsk)Inngår i: World Congress on Medical Physics and Biomedical Engineering: September 7 - 12, 2009, Munich, Germany / [ed] Olaf Dössel; Wolfgang C. Schlegel, Berlin: Springer Science+Business Media B.V., 2009, Vol. 7, s. 331-334Konferansepaper, Publicerat paper (Fagfellevurdert)
Abstract [en]

Prostate cancer is a major health problem among men in Europe and the USA. Tactile resonance technology and Raman spectroscopy have both shown promising results in vitro, detecting and diagnosing cancer tumors respectively. A new approach, combining the strength of resonance technology and Raman spectroscopy is investigated. This study deals with the effects of molding a Raman fiber optic probe into a cylindrical resonance sensor element (RSE) to achieve a combined probe. Heat induced by the Raman spectroscopy laser might affect temperature dependent properties of the RSE. Also, molding a Raman probe into a RSE will affect its properties. The RSE temperature dependency was investigated using the resonance sensor system Venustron®. The Raman fiber optic probe was simulated by a thin steel pipe which was molded into a single cylindrical RSE. The effects on the frequency characteristics when modifying the RSE were investigated with a network analyzer. Although the resonance frequency of a RSE is temperature dependent, the frequency shift, as used for calculating stiffness, is not noticeably affected by moderate temperature variations. The RSE properties change less by using a small amount of filler material and a small diameter of the Raman probe.

sted, utgiver, år, opplag, sider
Berlin: Springer Science+Business Media B.V., 2009. Vol. 7, s. 331-334
Serie
International Federation for Medical and Biological Engineering Proceedings, ISSN 1680-0737 ; 25
HSV kategori
Forskningsprogram
Medicinsk teknik för hälsovård
Identifikatorer
URN: urn:nbn:se:ltu:diva-40506Lokal ID: faa66910-a76c-11de-8293-000ea68e967bISBN: 978-3-642-03897-6 (tryckt)OAI: oai:DiVA.org:ltu-40506DiVA, id: diva2:1014028
Konferanse
World Congress on Medical Physics and Biomedical Engineering : 07/09/2009 - 12/09/2009
Merknad
Validerad; 2009; Bibliografisk uppgift: Vol. 7 med titel: Diagnostic and Therapeutic Instrumentation, Clinical Engineering; 20090922 (mornyb)Tilgjengelig fra: 2016-10-03 Laget: 2016-10-03 Sist oppdatert: 2017-11-25bibliografisk kontrollert

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Nyberg, MorganRamser, KerstinLindahl, Olof

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