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Technologies for localization and diagnosis of prostate cancer
Luleå tekniska universitet, Institutionen för system- och rymdteknik, Signaler och system.ORCID-id: 0000-0003-3268-1691
2009 (engelsk)Inngår i: Journal of Medical Engineering & Technology, ISSN 0309-1902, E-ISSN 1464-522X, Vol. 33, nr 8, s. 585-603Artikkel i tidsskrift (Fagfellevurdert) Published
Abstract [en]

The gold standard for detecting prostate cancer (PCa), systematic biopsy, lacks sensitivity as well as grading accuracy. PSA screening leads to over-treatment of many men, and it is unclear whether screening reduces PCa mortality. This review provides an understanding of the difficulties of localizing and diagnosing PCa. It summarizes recent developments of ultrasound (including elastography) and MRI, and discusses some alternative experimental techniques, such as resonance sensor technology and vibrational spectroscopy. A comparison between the different methods is presented. It is concluded that new ultrasound techniques are promising for targeted biopsy procedures, in order to detect more clinically significant cancers while reducing the number of cores. MRI advances are very promising, but MRI remains expensive and MR-guided biopsy is complex. Resonance sensor technology and vibrational spectroscopy have shown promising results in vitro. There is a need for large prospective multicentre trials that unambiguously prove the clinical benefits of these new techniques.

sted, utgiver, år, opplag, sider
2009. Vol. 33, nr 8, s. 585-603
HSV kategori
Forskningsprogram
Medicinsk teknik för hälsovård; Centrumbildning - Centrum för medicinsk teknik och fysik (CMTF)
Identifikatorer
URN: urn:nbn:se:ltu:diva-4331DOI: 10.3109/03091900903111966PubMedID: 19848851Scopus ID: 2-s2.0-70350492898Lokal ID: 242c1810-ae80-11de-8293-000ea68e967bOAI: oai:DiVA.org:ltu-4331DiVA, id: diva2:977195
Prosjekter
Prostatacancer
Merknad

Validerad; 2009; 20091001 (ysko)

Tilgjengelig fra: 2016-09-29 Laget: 2016-09-29 Sist oppdatert: 2024-03-26bibliografisk kontrollert

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Forlagets fulltekstPubMedScopushttp://informahealthcare.com/doi/abs/10.3109/03091900903111966

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Candefjord, StefanRamser, KerstinLindahl, Olof

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