Businesses wishing to make a positive impact face challenges related to the creation and dissemination of knowledge on their Corporate Social Responsibility (CSR) efforts. The challenges are twofold: first, they need to make responsibility part of the organization’s DNA, and second, they need to communicate this information to internal and external stakeholders. Responding to these challenges, this chapter provides an easy-to-follow and clear protocol to facilitate the creation of Sustainable Development Goals-driven CSR strategies and the management of CSR knowledge. This approach will enable firms to make CSR an inseparable part of their DNA and create and disseminate CSR knowledge more effectively among various stakeholders.