The Moa Bay lateritic Ni-Co mining district (eastern Cuba) has total mineral resources of 198.54 million metric tonnes (Mt) at 1.07% Ni and 0.12% Co. Laterite profiles from this district are characterized by their oxide-dominated ore zones. Laterite profiles from the Yagrumaje Norte, Punta Gorda, and Yamanigüey deposits contain average Ni and Co concentrations in the oxide zone of 0.88 and 0.12%. Goethite is the most abundant mineral in the oxide zone and the most important Ni-Co-Sc–bearing mineral, with median NiO, CoO, and Sc contents of 0.78 wt %, 0.07 wt %, and 58 ppm, respectively, and up to 2.77 wt %, 0.26 wt %, and 117 ppm. Maghemite is also widely present (avg of 5% and up to 19% modal proportion) and represents an important but largely ignored Ni- and Co-bearing ore phase, with median NiO and CoO concentrations of 2.11 and 0.25 wt %, respectively, and maximum values of 13.9 and 1.84 wt % each. Nickel and Co substitute for ferric iron in the structure of maghemite. Manganese oxyhydroxides (lithiophorite and lithiophorite-asbolane intermediate), which are also significant Ni-Co–bearing phases, have median NiO and CoO contents of 10.6 and 6.41 wt %, respectively. Some Mn oxyhydroxides, which formed after replacing goethite, also contain significant amounts of Sc (up to 94 ppm). Although most deposits in the Moa Bay lateritic district are classified as oxide type, Yamanigüey (avg Ni grade of 1.98%) is characterized by well-developed saprolite horizons, with secondary serpentine (serpentine II) and garnierite being the main Ni-bearing phases.