The effect of chemical variables on the kinetic parameters of apatite flotation from magnetite has been investigated. The two common first-order kinetic models reported in the literature, i.e., the model with rectangular distribution of floatabilities and the model with fast and slow-floating components (F-S model) have been applied in the evaluation of flotation results. The models are evaluated by fitting the flotation results from batch flotation tests. The results although indicate that both models describe the apatite flotation kinetics well in a wide range of kinetic parameters, the F-S model is found to be better in the goodness of fit to the results from every flotation test and also to describe the flotation performance adequately. The kinetic parameters of the F-S model are varied with a change in chemical variables. In particular, the rate constants ratio Kf/Ks is found to be an important parameter for achieving selectivity between apatite and magnetite, and the effect of reagents dosages on the ratio is discussed. The effect of particle size on the apatite flotation kinetics is also illustrated by analysing the froth products at each flotation time in different size classes.