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Inverkan av bröstdiagnostik med MR inför kirurgisk behandlning: En litteraturstudie
Luleå University of Technology, Department of Health Sciences.
Luleå University of Technology, Department of Health Sciences.
2018 (Swedish)Independent thesis Basic level (professional degree), 10 credits / 15 HE creditsStudent thesisAlternative title
The impact of breast MRI before surgical treatment : A litterature review (English)
Abstract [sv]

Inledning: Bröstcancer är en vanlig cancerform hos kvinnor och årligen drabbas 1,5 miljoner kvinnor världen över. Screeningprogram och tidig upptäckt är två faktorer som leder till ökad överlevnad. För kvinnor där en ökad cancerrisk föreligger såsom förhöjd ärftlighet och BRCA-mutation rekommenderar socialstyrelsen att mammografiscreening kompletteras med MR. MR kan komplettera bröstdiagnostik till en mer individanpassad behandling. Syftet: Syftet med denna litteraturstudie var att beskriva hur bröstdiagnostik med magnetkamera (MR) inverkar på den kirurgiska behandlingen av bröstcancer. Metod: En litteraturstudie genomfördes, där 11 kvantitativa artiklar användes för att svara på studiens syfte. Resultat: Preoperativ MR detekterade ytterligare maligna lesioner som inte tidigare var kända vilket medförde en förändrad behandling till mer omfattande kirurgi såsom mastektomi och lumpektomi. MR visade generellt en överskattning av tumörstorlek vid bedömning av tumörutbredning. Utöver den redan diagnostiserade bröstcancern detekterades med MR ytterligare lesioner vilka ej var synliga vid mammografi både i det primära och det kontralaterala bröstet. MR i kombination med biopsi konstaterar maligna lesioner. Slutsats: Fakta tyder på att MR har hög sensitivitet men en lägre specificitet vid detektering av förändringar i bröstvävnaden. Resultatet är ej entydigt och behov finns av ytterligare studier inom ämnet. 

Abstract [en]

Introduction: Breast cancer is a common form of cancer in women, annually, 1.5 million women are affected worldwide. Screening programs and early detection lead to increased survival. In women where there is increased cancer risk with increased heredity and in BRCA mutation, the National Board of Health recommends that mammography screening be supplemented with Magnetic resonance imaging (MRI). MRI can supplement breast diagnosis and can lead to a more personalized treatment. Purpose:The purpose of this literature study was to describe how breast diagnosis with MR affects the surgical treatment of breast cancer. Method: A literature study was conducted, where 11 quantitative articles were used to respond to the purpose of the study.Results: Preoperative MRI detected additional malignant lesions not previously known which resulted in a change in treatment for more extensive surgery such as mastectomy and lumpectomy. MRI generally showed an overestimate of tumor size in the assessment of tumor proliferation. In addition to the already diagnosed breast cancer, MR was detected additional lesions which were not visible in mammography in both the primary and the contralateral breast. MRI in combination with biopsy notes malignant lesions. Conclusion: Facts suggest that MRI has high sensitivity but a lower specificity in detecting changes in the breast tissue. The results are not unambiguous and there is a need for further studies on the subject.

Place, publisher, year, edition, pages
2018. , p. 26
Keywords [en]
magnetic resonance imaging, breast cancer, lesion, preoperative, surgical treatmen
Keywords [sv]
magnetresonanstomografi, bröstcancer, lesion, preoperativ, kirurgisk behandling
National Category
Radiology, Nuclear Medicine and Medical Imaging
Identifiers
URN: urn:nbn:se:ltu:diva-72350OAI: oai:DiVA.org:ltu-72350DiVA, id: diva2:1273375
Subject / course
Student thesis, at least 15 credits
Educational program
Diagnostic Radiology Nursing, bachelor's level
Supervisors
Examiners
Available from: 2018-12-21 Created: 2018-12-20 Last updated: 2018-12-21Bibliographically approved

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