The weldability of duplex stainless steels partly depends on the ferritization of the high-temperature heat-affected zone (HT-HAZ). This area is rather narrow, and it can be challenging to visualize and determine its actual impact on the properties. To address this, various methods were applied to study the grain growth and austenite reformation in the HT-HAZ of the lean duplex grade UNS S32101. Thermo-mechanical Gleeble® simulations were conducted at 1360 °C with different holding times and cooling rates. Subsequently, the grain size and ferrite content were measured on polished and etched cross-sections. Bead-on-plate welds were performed on the same heat of 6-mm plate thickness using the gas tungsten arc welding (GTAW) process. The shielding gas was Ar + 0–8% N2 to illustrate the effect of nitrogen additions on the HT-HAZ morphology. The arc was either stationary, welding at one spot for 0.5–120 s, or travelling at different speeds to generate varying heat inputs and temperature gradients. The thermo-mechanical simulations approximated the results obtained by travelling arc welding and allowed for a more comprehensive investigation. Stationary arc welding was not suitable for HT-HAZ studies as it quickly caused nitrogen depletion and resulted in significantly higher ferrite contents compared to the travelling arc welds.