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Identifying the intermolecular hydrogen-bonding supramolecular synthons in an indomethacin-nicotinamide cocrystal by solid-state NMR
University of Warwick.
University of Warwick.
Luleå University of Technology, Department of Civil, Environmental and Natural Resources Engineering, Sustainable Process Engineering.ORCID iD: 0000-0003-1067-7990
Luleå University of Technology, Department of Health Sciences, Medical Science.ORCID iD: 0000-0002-6050-0432
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2012 (English)In: Chemical Communications, ISSN 1359-7345, E-ISSN 1364-548X, Vol. 48, no 88, p. 10844-10846Article in journal (Refereed) Published
Abstract [en]

Two-dimensional 1H double-quantum and 14N- 1H & 1H- 13C heteronuclear magic-angle spinning (MAS) NMR spectra recorded at natural isotopic abundance identify specific intermolecular COOH⋯N arom and CH arom⋯OC hydrogen-bonding interactions in the solid-state structure of an indomethacin-nicotinamide cocrystal, thus additionally proving cocrystal formation.

Place, publisher, year, edition, pages
2012. Vol. 48, no 88, p. 10844-10846
National Category
Physical Chemistry Other Health Sciences
Research subject
Chemistry of Interfaces; Health Science
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URN: urn:nbn:se:ltu:diva-10739DOI: 10.1039/c2cc36094bISI: 000309666900007Scopus ID: 2-s2.0-84867346116Local ID: 995bd33e-23f7-410b-b3e4-7d422746aa5bOAI: oai:DiVA.org:ltu-10739DiVA, id: diva2:983686
Note
Validerad; 2012; 20121021 (ysko)Available from: 2016-09-29 Created: 2016-09-29 Last updated: 2018-07-10Bibliographically approved

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Antzutkin, OlegAlhalaweh, AmjadVelaga, Sitaram

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