Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Brain tumor modeling: glioma growth and interaction with chemotherapy
Tehran University of Medical Science.
Tehran University of Medical Science.
Tehran University of Medical Science.
University of Tehran.
Show others and affiliations
Number of Authors: 52011 (English)In: Proceedings of SPIE, the International Society for Optical Engineering, ISSN 0277-786X, E-ISSN 1996-756X, Vol. 8285Article in journal (Refereed) Published
Abstract [en]

In last decade increasingly mathematical models of tumor growths have been studied, particularly on solid tumors which growth mainly caused by cellular proliferation. In this paper we propose a modified model to simulate the growth of gliomas in different stages. Glioma growth is modeled by a reaction-advection-diffusion. We begin with a model of untreated gliomas and continue with models of polyclonal glioma following chemotherapy. From relatively simple assumptions involving homogeneous brain tissue bounded by a few gross anatomical landmarks (ventricles and skull) the models have been expanded to include heterogeneous brain tissue with different motilities of glioma cells in grey and white matter. Tumor growth is characterized by a dangerous change in the control mechanisms, which normally maintain a balance between the rate of proliferation and the rate of apoptosis (controlled cell death). Result shows that this model closes to clinical finding and can simulate brain tumor behavior properly.

Place, publisher, year, edition, pages
2011. Vol. 8285
National Category
Applied Mechanics
Research subject
Experimental Mechanics
Identifiers
URN: urn:nbn:se:ltu:diva-32986DOI: 10.1117/12.913432Local ID: 7b02a502-9fea-4067-8afc-68d9aa565e94OAI: oai:DiVA.org:ltu-32986DiVA, id: diva2:1006221
Conference
International Conference on Graphic and Image Processing (ICGIP 2011) : 01/10/2011
Available from: 2016-09-30 Created: 2016-09-30 Last updated: 2017-11-30Bibliographically approved

Open Access in DiVA

No full text in DiVA

Other links

Publisher's full texthttp://proceedings.spiedigitallibrary.org/proceeding.aspx?articleid=1197849

Authority records BETA

Khodadad, Davood

Search in DiVA

By author/editor
Khodadad, Davood
In the same journal
Proceedings of SPIE, the International Society for Optical Engineering
Applied Mechanics

Search outside of DiVA

GoogleGoogle Scholar

doi
urn-nbn

Altmetric score

doi
urn-nbn
Total: 15 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf