As part of a project within the Swedish nuclear industry with the objective to investigate the performance of different constitutive models in ratchet simulation, an extensive experimental program has been conducted on pressurized tube specimens. In total 30 test specimens made of two different materials, 316L and P235, have been manufactured and tested. In order to determine material properties, monotonic tensile load and internal pressure experiments have been performed. The remaining test specimens have been used for ratcheting experiments. The experimental results show ratcheting in the hoop direction when the tube is subjected to certain combinations of internal pressure and cyclic axial strains. The higher the pressure is and the larger the strain ranges are, the higher the ratcheting response becomes. Measured ratcheting strains are compared to numerical simulations using different constitutive models. In this paper the interrelated models of Prager, Armstrong-Frederick and Chaboche are investigated. In addition to these, the Besseling model is investigated. Based on the result from this investigation, recommendations on how to conduct ratcheting simulation of pressurized equipment subjected to cyclic secondary loading are presented.