Cancer detection probe combining Raman and resonance sensor technology: experimental study on temperature dependence and effects of molding
2009 (English)In: World Congress on Medical Physics and Biomedical Engineering: September 7 - 12, 2009, Munich, Germany / [ed] Olaf Dössel; Wolfgang C. Schlegel, Berlin: Springer Science+Business Media B.V., 2009, Vol. 7, 331-334 p.Conference paper (Refereed)
Prostate cancer is a major health problem among men in Europe and the USA. Tactile resonance technology and Raman spectroscopy have both shown promising results in vitro, detecting and diagnosing cancer tumors respectively. A new approach, combining the strength of resonance technology and Raman spectroscopy is investigated. This study deals with the effects of molding a Raman fiber optic probe into a cylindrical resonance sensor element (RSE) to achieve a combined probe. Heat induced by the Raman spectroscopy laser might affect temperature dependent properties of the RSE. Also, molding a Raman probe into a RSE will affect its properties. The RSE temperature dependency was investigated using the resonance sensor system Venustron®. The Raman fiber optic probe was simulated by a thin steel pipe which was molded into a single cylindrical RSE. The effects on the frequency characteristics when modifying the RSE were investigated with a network analyzer. Although the resonance frequency of a RSE is temperature dependent, the frequency shift, as used for calculating stiffness, is not noticeably affected by moderate temperature variations. The RSE properties change less by using a small amount of filler material and a small diameter of the Raman probe.
Place, publisher, year, edition, pages
Berlin: Springer Science+Business Media B.V., 2009. Vol. 7, 331-334 p.
International Federation for Medical and Biological Engineering Proceedings, ISSN 1680-0737 ; 25
Research subject Medical Engineering for Healthcare
IdentifiersURN: urn:nbn:se:ltu:diva-40506Local ID: faa66910-a76c-11de-8293-000ea68e967bISBN: 978-3-642-03897-6 (print)OAI: oai:DiVA.org:ltu-40506DiVA: diva2:1014028
World Congress on Medical Physics and Biomedical Engineering : 07/09/2009 - 12/09/2009
Validerad; 2009; Bibliografisk uppgift: Vol. 7 med titel: Diagnostic and Therapeutic Instrumentation, Clinical Engineering; 20090922 (mornyb)2016-10-032016-10-03Bibliographically approved