E-health has the potential to improve health care service deliveries in developing countries that are associated with poor access to health facilities due to lack of proper transportation systems, lack of adequate resources in terms of finances and personnel in the health sector. Many developed countries like the Unites States of America and the European Union member states have implemented e-health solutions in their health sectors to improve health services through improved access to medical information be it Electronic Health Records (EHR) or administrative information. Developing countries are also implementing e-health in their health sectors in trying to improve health services through use of ICT. However, developing countries are lacking in a lot of necessities of e-health in terms of electrical and ICT infrastructures, money, credible political backing, meaningful administrative regulations, and local human resources. Most e-health solutions keep data like the electronic health records which is very sensitive and confidential and security of such data need to be properly managed in order to preserve its Confidentiality, Integrity and Availability. Now as developing countries embark on e-health in their health sectors, with all the challenges they are facing, what are the best practices to be followed for security management of their e-health solutions? This is the focus of my research as it tries to come up with best practices for security management of e-health solutions in developing countries.