The activities of methanol, ethanol, 2-propanol, and 1-butanol in poly(ethylene glycol) methacrylate (Mn = 360) solutions have been measured by the isopiestic method at 298.15 K. Sodium iodide and calcium chloride were used as the isopiestic standards for the calculation of activities. The original equation of Flory−Huggins and the modified Flory−Huggins equation with concentration-dependent interaction parameters have been used for the correlation of the experimental solvent activity data. The strength of interaction between different alcohols and the polymer was discussed on the basis of the obtained Flory−Huggins interaction parameters. The reliability of the two local-composition models, NRTL and NRF, were also assessed by fitting the experimental activity data to these models. All of these models satisfactorily present the obtained experimental activity data