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Novel Nanostructured Polymeric Carriers to Enable Drug Delivery for Cardiovascular Diseases
Department of Pharmaceutical Sciences and Technology, University of Chile.
Department of Pharmaceutical Sciences and Technology, University of Chile.
Department of Pharmaceutical Sciences and Technology, University of Chile.
Department of Biochemistry & Molecular Biology, University of Chile.
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2015 (English)In: Current pharmaceutical design, ISSN 1381-6128, E-ISSN 1873-4286, Vol. 21, no 29, 4276-4284 p.Article in journal (Refereed) Published
Abstract [en]

Applications of polymeric nanotechnologies for enabling therapies for cardiovascular diseases have shown recent success. Both intravenous and oral administration have been investigated and achieved different degrees of development. While circulating polymeric nanostructured carriers are subjected to a number of interactions, smart nanoparticle design has enabled the formulation of active molecules to be delivered to specific targets for cardiovascular effects. This review aims at outlining the multiple factors that can affect the fate of polymeric nanostructured carriers in systemic circulation. With an understanding of these factors, the literature on the various polymeric nanostructured carriers is reviewed. Finally, the emerging uses of nanotechnology to formulate orally administered drugs for cardiovascular diseases are depicted.

Place, publisher, year, edition, pages
2015. Vol. 21, no 29, 4276-4284 p.
National Category
Pharmaceutical Sciences Other Health Sciences
Research subject
Health Science
Identifiers
URN: urn:nbn:se:ltu:diva-64680PubMedID: 26323423Scopus ID: 2-s2.0-84945921420OAI: oai:DiVA.org:ltu-64680DiVA: diva2:1118586
Available from: 2017-06-30 Created: 2017-06-30 Last updated: 2017-07-06Bibliographically approved

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