A 4-component model for settling slurry pipeline friction loss has been previously described by Wilson and Sellgren. The goal of the present work was to collect a comprehensive and accurate data set spanning multiple flow regimes for the purpose of validating and calibrating the model. This was accomplished by obtaining four different graded silica and crushed granite products representing the four model components. These were then combined and tested in permutations from the individual components to the complete mixture at various concentrations. Primary experiments were carried out in a 203 mm (8 inch) pipeline with selected corresponding experiments repeated in a 103 mm (4 inch) pipeline for validation of pipe size scaling. In all, 40 tests were performed with particle sizes ranging from minus 40 m to 12.5 mm, d50 particle sizes from minus 40 μm to 7.5 mm, and delivered solids concentrations from 4% to 38% by volume. Particle size distributions varied from very narrow to very broad, with d85/d50 ratios ranging from 1.3 to 30. Analysis of the data suggested the introduction of two new correlating factors which have resulted in good agreement between the comprehensive data set and the revised model.