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A population-based cohort of adults with asthma: mortality and participation in a long-term follow-up
Department of Public Health and Clinical Medicine, Division of Occupational and Environmental Medicine, The OLIN Unit, Umeå University.
Luleå University of Technology, Department of Health Sciences, Nursing Care.ORCID iD: 0000-0002-1630-3167
Luleå University of Technology, Department of Health Sciences, Nursing Care.ORCID iD: 0000-0001-6622-3838
Department of Public Health and Clinical Medicine, Occupational and Environmental Medicine, The OLIN Unit, Umeå University.
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2017 (English)In: European Clinical Respiratory Journal, ISSN 2001-8525, Vol. 4, no 1, 1334508Article in journal (Refereed) Published
Abstract [en]

Background and objective: Asthma is a major public health concern. The aim of this study was to characterize a large population-based cohort of adults with asthma, and to study factors associated with all-cause mortality and non-participation in a long-term follow-up. Design: Random and stratified samples from five population-based cohorts were clinically examined during 1986-2001, and all subjects with asthma were included in the study (n = 2055, age 19-72 years, 55% women). Independent associations between different risk factors and (i) mortality and (ii) non-participation in a clinical follow-up in 2012-2014 were estimated. Results: In 1986-2001, 95% reported any wheeze and/or attacks of shortness of breath in the past 12 months, and/or asthma medication use. Over the up to 28 years of follow-up time, the cumulative mortality was 22.7%. Male gender, current smoking, and lower forced expiratory volume in 1 sec of predicted (FEV1% of predicted) were independent risk factors for mortality, while obesity was associated with non-participation in the follow-up. Older ages, ischemic heart disease, and low socioeconomic status were associated with both mortality and non-participation. Conclusions: The risk factors associated with mortality in this adult population-based asthma cohort were similar to those commonly identified in general population samples, i.e. male gender, current smoking, and lower FEV1% of predicted, while obesity was associated with non-participation in a long-term follow-up. Ischemic heart disease, low socioeconomic status, and older ages were associated with both mortality and non-participation.

Place, publisher, year, edition, pages
Taylor & Francis, 2017. Vol. 4, no 1, 1334508
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Nursing
Research subject
Nursing
Identifiers
URN: urn:nbn:se:ltu:diva-65110DOI: 10.1080/20018525.2017.1334508ISI: 000403663400001PubMedID: 28680543OAI: oai:DiVA.org:ltu-65110DiVA: diva2:1133425
Note

Validerad; 2017; Nivå 2; 2017-08-15 (andbra)

Available from: 2017-08-15 Created: 2017-08-15 Last updated: 2017-08-22Bibliographically approved

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