Blast-induced fragmentation has a significant influence on the operational efficiency of open pit mines, especially on loading and crushing, the two immediate tasks after blasting. This study presents an empirical method to determine the target fragmentation for efficient loading and crushing at the Aitik mine in Sweden. In the study, the loading efficiency of rope shovels was correlated to the energy consumption and throughput of a gyratory crusher. Two photographic techniques were utilized to assess the feed fragmentation, considering the lithological origin of the ore as an indicator of hardness. The results indicate ore hardness is most influential in mid-range fragmentation, with a marginal effect in coarser fragmentations. The influence of fragmentation is more pronounced in the coarse region, with a sudden reduction in efficiency for P80 values coarser than 800 mm. The results suggest tailoring the fragmentation to a P80 of 600-800 mm could lead to higher operational efficiency at Aitik.