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Effect of Cholesterol and Curcumin on Ordering of DMPC Bilayers
Institute of Physics, Kazan Federal University, Kazan, Russia.
Institute of Physics, Kazan Federal University, Kazan, Russia.
Institute of Physics, Kazan Federal University, Kazan, Russia;Kazan State Medical University, Kazan, Russia.
Luleå University of Technology, Department of Civil, Environmental and Natural Resources Engineering, Chemical Engineering.ORCID iD: 0000-0003-1067-7990
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2019 (English)In: Applied Magnetic Resonance, ISSN 0937-9347, E-ISSN 1613-7507, Vol. 50, no 1-3, p. 511-520Article in journal (Refereed) Published
Abstract [en]

In this work, we compared the effects of curcumin and cholesterol directly competing to insert into the DMPC lipid bilayer during bilayer formation from an initially non-ordered state. 2H and 14N nuclear magnetic resonance spectroscopy showed that curcumin is not embedded deep in the lipid bilayer and interacts mainly with the head group of the lipid. In a more complex system of DMPC/CHOL/CUR, curcumin amplifies the effect of cholesterol on the ordering of lipid acyl chains.

Place, publisher, year, edition, pages
Springer, 2019. Vol. 50, no 1-3, p. 511-520
National Category
Physical Chemistry
Research subject
Chemistry of Interfaces
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URN: urn:nbn:se:ltu:diva-72752DOI: 10.1007/s00723-018-1102-2ISI: 000458124800036Scopus ID: 2-s2.0-85057198967OAI: oai:DiVA.org:ltu-72752DiVA, id: diva2:1284332
Note

Validerad;2019;Nivå 2;2019-03-08 (johcin)

Available from: 2019-01-31 Created: 2019-01-31 Last updated: 2019-03-08Bibliographically approved

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Antzutkin, OlegFilippov, Andrei

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