The zeta potential of single and multi‐inorganic fine particle mixtures (hematite and gangues, i.e., SiO₂+Al₂O₃) with Na‐bentonite was investigated to understand and properly control the mineral surface properties relevant to pelletization of low grade fine iron ores. The zeta potential of hematite‐bentonite mixture showed more negative charge up to 1wt.% bentonite dosage and became constant. In the multi‐particle mixture systems with bentonite, the SiO₂ amount in the system controlled the changes in zeta potential due to its high negative charge (‐54.9 mV at natural pH) and the bentonite attachment on its surface based on the electrostatic interaction while Al₂O₃ had no effect due to its negligible surface charge (‐1.6 mV at natural pH). This paper reports the new insight into the characterization of surface chemistry of inorganic/mineral mixture systems to understand their surface charge properties in relation to fine mineral particle processing, and to show a direction towards the elucidation of particle dispersion/aggregation mechanism in complex ore systems aiming for their beneficiations.