Life-years lost due to asthma and COPDShow others and affiliations
2020 (English)In: European Respiratory Journal, ISSN 0903-1936, E-ISSN 1399-3003, Vol. 56, no Suppl 64, article id 1400Article in journal, Meeting abstract (Other academic) Published
Abstract [en]
Background: Quality-adjusted life-years (QALYs) is commonly used in health-economic evaluations. QALY-weights combine health status and time into one measure.
Aims: To investigate the association between multimorbidity and QALY-weights among adults with asthma and COPD.
Methods: Within the OLIN-studies in northern Sweden, a random sample was invited to a postal questionnaire survey. A random sample of 1016 responders was invited to clinical examinations and interviews in 2009 (737 participated, ages 21-86 years), of which 605 completed the health-related quality of life (HRQL) questionnaire SF-36. QALY-weights were derived from the SF-36 data using the SF-6D tool via the standard gamble method. The SF-6D scores are equivalent to QALY-weights with low values representing poor health and the score one representing perfect health.
Results: Of the 605 participants, 74 had current asthma, 81 had COPD (FEV1/FVC<0.7), 66 had heart disease, 30 had diabetes, 30 had rheumatic disease, and 160 had hypertension. There was an association between an increasing number of morbid conditions and lower QALY-weights (p<0.001). The mean QALY-weight tended to be lower among subjects with asthma compared to COPD, 0.77 and 0.81, respectively (p=0.078). Subjects with COPD and two or more non-respiratory conditions had significantly lower QALY-weights compared to subjects with COPD alone (0.75 vs.0.83, p=0.016). No significant difference in QALY-weights was found among asthmatics with versus without other non-respiratory conditions.
Conclusions: Subjects with asthma tended to have lower QALY-weights compared to subjects with COPD. Having two or more non-respiratory conditions affected the QALY-weight negatively among subjects with COPD but not among subjects with asthma.
Place, publisher, year, edition, pages
European Respiratory Society (ERS) , 2020. Vol. 56, no Suppl 64, article id 1400
Keywords [en]
Quality of life, Asthma, Asthma - diagnosis
National Category
Nursing
Research subject
Nursing
Identifiers
URN: urn:nbn:se:ltu:diva-82902DOI: 10.1183/13993003.congress-2020.1400ISI: 000606501402366OAI: oai:DiVA.org:ltu-82902DiVA, id: diva2:1527670
Conference
ERS International Congress, 6-9 September, 2020, Virtual
Note
Godkänd;2021;Nivå 0;2021-02-11 (alebob)
2021-02-112021-02-112022-11-16Bibliographically approved