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Performance analysis of seven Convolutional Neural Networks (CNNs) with transfer learning for Invasive Ductal Carcinoma (IDC) grading in breast histopathological images
Department of Mechatronics and Biomedical Engineering, Lee Kong Chian Faculty of Engineering and Science, Universiti Tunku Abdul Rahman, Sungai Long, Malaysia.
Department of Mechatronics and Biomedical Engineering, Lee Kong Chian Faculty of Engineering and Science, Universiti Tunku Abdul Rahman, Sungai Long, Malaysia.
Department of Mechatronics and Biomedical Engineering, Lee Kong Chian Faculty of Engineering and Science, Universiti Tunku Abdul Rahman, Sungai Long, Malaysia.
Department of Electrical and Electronic Engineering, Lee Kong Chian Faculty of Engineering and Science, Universiti Tunku Abdul Rahman, Sungai Long, Malaysia.
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2022 (English)In: Scientific Reports, E-ISSN 2045-2322, Vol. 12, article id 19200Article in journal (Refereed) Published
Abstract [en]

Computer-aided Invasive Ductal Carcinoma (IDC) grading classification systems based on deep learning have shown that deep learning may achieve reliable accuracy in IDC grade classification using histopathology images. However, there is a dearth of comprehensive performance comparisons of Convolutional Neural Network (CNN) designs on IDC in the literature. As such, we would like to conduct a comparison analysis of the performance of seven selected CNN models: EfficientNetB0, EfficientNetV2B0, EfficientNetV2B0-21k, ResNetV1-50, ResNetV2-50, MobileNetV1, and MobileNetV2 with transfer learning. To implement each pre-trained CNN architecture, we deployed the corresponded feature vector available from the TensorFlowHub, integrating it with dropout and dense layers to form a complete CNN model. Our findings indicated that the EfficientNetV2B0-21k (0.72B Floating-Point Operations and 7.1 M parameters) outperformed other CNN models in the IDC grading task. Nevertheless, we discovered that practically all selected CNN models perform well in the IDC grading task, with an average balanced accuracy of 0.936 ± 0.0189 on the cross-validation set and 0.9308 ± 0.0211on the test set.

Place, publisher, year, edition, pages
Springer Nature, 2022. Vol. 12, article id 19200
National Category
Computer graphics and computer vision
Research subject
Machine Learning
Identifiers
URN: urn:nbn:se:ltu:diva-94180DOI: 10.1038/s41598-022-21848-3ISI: 000881825800096PubMedID: 36357456Scopus ID: 2-s2.0-85141622244OAI: oai:DiVA.org:ltu-94180DiVA, id: diva2:1712758
Note

Validerad;2022;Nivå 2;2022-11-22 (hanlid);

Funder: Fundamental Research Grant Scheme (FRGS/1/2019/ICT04/UTAR/02/1, vote account no: 8073/Y01); Universiti Tunku Abdul Rahman Research Fund (IPSR/RMC/UTARRF/2022-C1/H01)

Available from: 2022-11-22 Created: 2022-11-22 Last updated: 2025-02-07Bibliographically approved

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