Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Retention model for the resolved enantiomers of felodipine on chiral-AGP using micellar mobile phases
Department of Analytical Pharmaceutical Chemistry, Uppsala University, Biomedical Centre, Uppsala, Sweden.
Department of Analytical Pharmaceutical Chemistry, Uppsala University, Biomedical Centre, Uppsala, Sweden.
Department of Analytical Pharmaceutical Chemistry, Uppsala University, Biomedical Centre, Uppsala, Sweden.
1995 (English)In: Chirality, ISSN 0899-0042, E-ISSN 1520-636X, Vol. 7, no 1, p. 23-27Article in journal (Refereed) Published
Abstract [en]

A retention model for the chiral separation of an uncharged solute, felodipine, on CHIRAL-AGP, using a micellar mobile phase is proposed. The model assumes the presence of two stereoselective sites and each enantiomer was found to interact with different sites. Addition of a chiral aliphatic alcohol, (+)-(S)-2-octanol, preferentially interacted with the binding site for (-)-(S)-felodipine. The monomeric form of the micellar agent (Tween® 20) competed with the enantiomers for the adsorption sites, and the formation of a 1:1 complex between the enantiomers and the micelles was assumed. The retention of the solutes was effectively controlled by adding small quantities (

Place, publisher, year, edition, pages
1995. Vol. 7, no 1, p. 23-27
Identifiers
URN: urn:nbn:se:ltu:diva-2619DOI: 10.1002/chir.530070105Local ID: 042982e0-ec49-11dd-99cd-000ea68e967bOAI: oai:DiVA.org:ltu-2619DiVA, id: diva2:975472
Note

Godkänd; 1995; 20090127 (andbra)

Available from: 2016-09-29 Created: 2016-09-29 Last updated: 2018-01-12Bibliographically approved

Open Access in DiVA

No full text in DiVA

Other links

Publisher's full text

Authority records BETA

Haupt, Dan

Search in DiVA

By author/editor
Haupt, Dan
In the same journal
Chirality

Search outside of DiVA

GoogleGoogle Scholar

doi
urn-nbn

Altmetric score

doi
urn-nbn
Total: 69 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf