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Investigation of wear and wear Particles from a UHMWPE/multi-walled carbon nanotube nanocomposite for total joint replacements
Luleå University of Technology, Department of Engineering Sciences and Mathematics, Machine Elements.
Institute of Medical and Biological Engineering, Leeds, UK.
Institute of Medical and Biological Engineering, Leeds, UK.
Institute of Medical and Biological Engineering, Leeds, UK.
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2014 (English)In: Wear, ISSN 0043-1648, E-ISSN 1873-2577, Vol. 317, no 1-2, p. 163-169Article in journal (Refereed) Published
Abstract [en]

Ultra high molecular weight polyethylene (UHMWPE) has been extensively used as a bearing surface in joint prostheses. However, wear debris generated from this material has been associated with osteolysis and implant loosening. Alternative materials, such as polymer composites, have been investigated due to their exceptional mechanical properties. The goal of the present work was to investigate the wear rate, size and volume distributions, bioactivity and biocompatibility of the wear debris generated from a UHMWPE/Multi-walled carbon nanotube (MWCNT) nanocomposite material compared with conventional UHMWPE. The results showed that the addition of MWCNTs led to a significant reduction in wear rate. Specific biological activity and functional biological activity predictions showed that wear particles from the UHMWPE/MWCNT nanocomposite had a reduced osteolytic potential compared to those produced from the conventional polyethylene. In addition, clinically relevant UHMWPE/MWCNT wear particles did not show any adverse effects on the L929 fibroblast cell viability at any of the concentrations tested over time. These findings suggest that UHMWPE/MWCNT nanocomposites represent an attractive alternative for orthopaedic applications.

Place, publisher, year, edition, pages
2014. Vol. 317, no 1-2, p. 163-169
National Category
Other Mechanical Engineering
Research subject
Machine Elements; Centre - Centre for Biomedical Engineering and Physics (CMTF)
Identifiers
URN: urn:nbn:se:ltu:diva-3538DOI: 10.1016/j.wear.2014.05.014ISI: 000341340700016Scopus ID: 2-s2.0-84902965814Local ID: 15e27770-b297-449d-b61a-3ea0312f34d1OAI: oai:DiVA.org:ltu-3538DiVA, id: diva2:976396
Note

Validerad; 2014; 20140617 (andbra)

Available from: 2016-09-29 Created: 2016-09-29 Last updated: 2025-02-14Bibliographically approved

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Suñer, SilviaEmami, Nazanin

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