ObjectiveTo evaluate the feasibility and possible effects of whole-body vibration (WBV) training on muscle strength and gait performance in people with late effects of polio.DesignA case-controlled pilot study with assessments before and after training.SettingA university hospital rehabilitation department.ParticipantsPeople (N=5; 3 men, 2 women; mean age, 64±6.7y; range, 55-71y) with clinically and electrophysiologically verified late effects of polio.InterventionsAll participants underwent 10 sessions of supervised WBV training (standing with knees flexed 40°-55° up to 60 seconds per repetition and 10 repetitions per session twice weekly for 5 weeks).Main Outcome MeasuresIsokinetic and isometric knee muscle strength (dynamometer), and gait performance (Timed Up & Go, Comfortable Gait Speed, Fast Gait Speed, and six-minute walk tests).ResultsAll participants completed the 5 weeks of WBV training, with no discernible discomfort. No significant changes in knee muscle strength or gait performance were found after the WBV training period.ConclusionsThis pilot study did not show any significant improvements in knee muscle strength and gait performance following a standard protocol of WBV training. Thus, the results do not lend support to WBV training for people with late effects of polio.