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Assessment of autonomic nerve function in myotonic dystrophy
Department of Internal Medicine, University Hospital, Umeå.
Department of Internal Medicine, University Hospital, Umeå.
Department of Internal Medicine, University Hospital, Umeå.
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1990 (English)In: Journal of the Autonomic Nervous System, ISSN 0165-1838, E-ISSN 1872-7476, Vol. 29, no 3, p. 187-192Article in journal (Refereed) Published
Abstract [en]

The function of the autonomic nervous system was studied in 23 patients with myotonic dystrophy, from a defined population in northern Sweden with an extremely high prevalence of this disease. Heart rate variability tests showed only minor signs of parasympathetic dysfunction. Blood pressure and plasma noradrenaline measurements in recumbent and upright positions showed no signs of sympathetic neuropathy. Increased plasma levels of noradrenaline was an unexpected finding. Our study does not support the hypothesis that cardiac arrhythmias, orthostatic hypotension, gastrointestinal motility disturbances and urinary bladder dysfunction in myotonic dystrophy are caused by autonomic neuropathy, and we believe that these symptoms should rather be ascribed to a defective function of the target organs

Place, publisher, year, edition, pages
1990. Vol. 29, no 3, p. 187-192
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URN: urn:nbn:se:ltu:diva-4151Local ID: 20b16730-9d85-11db-8975-000ea68e967bOAI: oai:DiVA.org:ltu-4151DiVA, id: diva2:977015
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Upprättat; 1990; 20070106 (lotfra)Available from: 2016-09-29 Created: 2016-09-29 Last updated: 2017-11-24Bibliographically approved

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Andersson, Staffan

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