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Asthma/COPD drugs reflecting disease prevalence, patient adherence and persistence
NEPI Foundation.
Luleå University of Technology, Department of Health Sciences, Medical Science.
NEPI Foundation.
Hospital Pharmacy, Ryhov.
2009 (English)In: Expert Review of Respiratory Medicine, ISSN 1747-6348, Vol. 3, no 1, p. 93-101Article in journal (Refereed) Published
Abstract [en]

The aim of this review is to discuss the methodological issues involved in using pharmacy-record databases of drug sales in pharmacoepidemiology and to illustrate the usefulness of such data in estimating disease prevalence, patient adherence and persistence to therapy. Recent studies show that asthma/chronic obstructive pulmonary disease (COPD) prevalence increases with age. The volume of acquired asthma/COPD drugs per patient also increases with age and was approximately 2.5-times higher for patients aged 60-69 years compared with patients aged 20-29 years. Despite this, there is a comparatively low interest in asthma/COPD research involving elderly individuals. Published asthma/COPD-prevalence data and drug-treatment-prevalence data correspond reasonably well. Short- as well as long-term studies on drug acquisition indicate that approximately a third of patients have drugs available to cover at least 80% of the prescribed treatment time. Only approximately a tenth of the patients acquired steroids or steroid combinations, corresponding to one daily defined dose per day over a 5-year treatment period. It is probable that asthma/COPD is undertreated in all age groups.

Place, publisher, year, edition, pages
2009. Vol. 3, no 1, p. 93-101
Identifiers
URN: urn:nbn:se:ltu:diva-4665DOI: 10.1586/17476348.3.1.93Scopus ID: 2-s2.0-70049107919Local ID: 2a4e39b0-ec63-11dd-99cd-000ea68e967bOAI: oai:DiVA.org:ltu-4665DiVA, id: diva2:977539
Note

Godkänd; 2009; 20090127 (andbra)

Available from: 2016-09-29 Created: 2016-09-29 Last updated: 2018-07-10Bibliographically approved

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Haupt, Dan

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