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Photoacoustic waves generated in blood studied using pulsed digital holography
Luleå University of Technology, Department of Engineering Sciences and Mathematics, Fluid and Experimental Mechanics.
2010 (English)In: Applied Optics, ISSN 1559-128X, E-ISSN 2155-3165, Vol. 49, no 16, p. 3053-3058Article in journal (Refereed) Published
Abstract [en]

We studied photoacoustic waves using pulsed digital holography. The acoustic waves were generated in a reindeer blood target by absorption of an IR laser pulse, λ=1064 nm and pulse length=12 ns. The acoustic pressure waves were then imaged in water using a second collimated laser pulse at λ=532 nm2 μs after the first IR pulse. Quantitative information on acoustic wave properties such as three-dimensional shape and pressure distribution was calculated by applying the inverse Radon transform on the recorded projection. The pressure pulse had a flat and sharp front parallel with the blood surface, which indicates that the pressure was generated at the blood surface. The generated pressure was proportional to the laser fluence with the proportionality constant equal to 1.8±0.3 cm-1. According to existing data, the proportionality constant should be 1.4 cm-1 for oxygenated human blood, which made our calculations probable

Place, publisher, year, edition, pages
2010. Vol. 49, no 16, p. 3053-3058
National Category
Applied Mechanics
Research subject
Experimental Mechanics; Centre - Centre for Biomedical Engineering and Physics (CMTF)
Identifiers
URN: urn:nbn:se:ltu:diva-6473DOI: 10.1364/AO.49.003053ISI: 000278265600012PubMedID: 20517375Scopus ID: 2-s2.0-77956004088Local ID: 4b2f7a20-6e3c-11df-ab16-000ea68e967bOAI: oai:DiVA.org:ltu-6473DiVA, id: diva2:979358
Note

Validerad; 2010; 20100602 (erka)

Available from: 2016-09-29 Created: 2016-09-29 Last updated: 2024-04-03Bibliographically approved

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Olsson, ErikGren, PerSjödahl, Mikael

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