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Elevated glucose levels in early puerperium, and association with high cortisol levels during parturition
Luleå University of Technology, Department of Health Sciences, Health and Rehab.ORCID iD: 0000-0001-9506-2930
Sveriges Lantbruksuniversitet, Swedish Centre for Animal Welfare, Swedish University of Agricultural Sciences, Uppsala.
Västerås Hospital.
Department of Medical Sciences, Uppsala University.
2016 (English)In: Scandinavian Journal of Clinical and Laboratory Investigation, ISSN 0036-5513, E-ISSN 1502-7686, Vol. 76, no 4, p. 309-312Article in journal (Refereed) Published
Abstract [en]

Background Gestational diabetes is one of the commonest metabolic problems associated with pregnancy and an accurate diagnosis is critical for the care. Research has shown that pregnant women have high levels of cortisol during the last stage of parturition. As cortisol is a diabetogenic hormone causing increased glucose levels, we wanted to study the association between cortisol and glucose levels during parturition. Materials and methods Glucose and cortisol were analyzed during parturition in 50 females divided according to slow (n = 11) and normal labors (n = 39). Blood samples were analyzed three times during the parturition and four times in the first day after delivery. Glucose levels were also measured once in each trimester. Results In the normal group, the glucose concentration increased from 6.2 (IQR 5.6-8.0) mmol/L in the latency phase to 11.6 (10.0-13.3) mmol/L at aftercare (p < 0.05). After parturition the glucose concentrations decreased gradually. There were significant Spearman rank correlations between glucose and cortisol values. Conclusions The changes associated with birth cause significant elevations of cortisol and glucose around parturition

Place, publisher, year, edition, pages
2016. Vol. 76, no 4, p. 309-312
National Category
Other Health Sciences
Research subject
Health Science
Identifiers
URN: urn:nbn:se:ltu:diva-7741DOI: 10.3109/00365513.2016.1149881ISI: 000380126500006PubMedID: 26985979Scopus ID: 2-s2.0-84961199267Local ID: 6279fca6-a115-4016-bcd0-0e4af1098b4eOAI: oai:DiVA.org:ltu-7741DiVA, id: diva2:980631
Note

Validerad; 2016; Nivå 2; 20160321 (andbra)

Available from: 2016-09-29 Created: 2016-09-29 Last updated: 2018-07-10Bibliographically approved

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