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Volatile rapid sequence induction in morbidly obese patients
Sunderby Hospital, Department of Anaesthesiolofy & Intensive Care.
Umea University, Department of Surgery & Perioperative Science, Department fo Cardiothorac Anaesthesia.
Umea University, Department of Surgery & Perioperative Science, Department fo Cardiothorac Anaesthesia.
Luleå University of Technology, Department of Health Sciences, Medical Science.
2011 (English)In: European Journal of Anaesthesiology, ISSN 0265-0215, E-ISSN 1365-2346, Vol. 28, no 11, p. 781-787Article in journal (Refereed) Published
Abstract [en]

Background and objective The interest in bariatric surgery is growing. Morbidly obese patients have an increased risk of hypoxia and decreased blood pressure during rapid sequence induction (RSI). Alternate RSI methods that provide cardiovascular and respiratory stability are required. With this in mind, we evaluated a method for volatile RSI in morbidly obese patients. Design Observational study. Methods Thirty-four patients with mean BMI 42.4 kg m(-2) undergoing bariatric surgery (morbidly obese group) and 22 patients with mean BMI 25.6 kg m(-2) as a control group were included in the study. Anaesthesia was induced with sevoflurane, propofol, suxamethonium and alfentanil, designed to avoid respiratory and haemodynamic adverse events and to minimise depressing effect on the brain respiratory centre under ongoing RSI. Peripheral oxygen saturation (SpO(2)) and mean arterial blood pressure were registered before and after endotracheal intubation. In addition, two time periods were measured during RSI: spontaneous breathing time (SBT) and apnoea time. Results We found no significant differences between the groups. No periods of desaturation were detected. SpO(2) was 100% before and after endotracheal intubation in all patients. Mean arterial pressure was maintained at a stable level in both groups. Mean SBT and apnoea time were 65.6 and 45.8 s in the morbidly obese group, and 70.7 and 47.7 s in the control group, respectively.

Place, publisher, year, edition, pages
2011. Vol. 28, no 11, p. 781-787
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Other Health Sciences
Research subject
Health Science
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URN: urn:nbn:se:ltu:diva-7852DOI: 10.1097/EJA.0b013e328348a9a5ISI: 000295865300006PubMedID: 21885982Scopus ID: 2-s2.0-80455141587Local ID: 64585b1c-50b3-45d6-b6cd-ad68a391a966OAI: oai:DiVA.org:ltu-7852DiVA, id: diva2:980742
Note

Validerad; 2011; 20111028 (andbra)

Available from: 2016-09-29 Created: 2016-09-29 Last updated: 2018-07-10Bibliographically approved

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