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Effect size underestimates the effects of interventions among older people with severe physical or cognitive impairments?
Luleå University of Technology, Department of Health Sciences, Health and Rehab.
2007 (English)In: Journal of The American Geriatrics Society, ISSN 0002-8614, E-ISSN 1532-5415, Vol. 55, no 8, p. 1315-1316Article in journal, Letter (Other academic) Published
Abstract [en]

The use of effect sizes for comparison of the effects of various studies could potentially underestimate the effect among older people with severe physical or cognitive impairment. In a Cochrane Review about strength training in older adults, Standardized Mean Difference (SMD) was used to estimate the effect on lower-limb strength, calculated as the difference in means (between the intervention and the control group) of the outcome divided by the standard deviation of the outcome. Using a calculation where the effect is divided by the variation in ability between participants may underestimate the effect in studies which have broad inclusion criteria (often the case in studies on older people with severe impairments) since the same change over time in the absolute value of an outcome will produce a higher effect size in a more homogeneous group, as is to be expected if the participants are more healthy. However, this seems not to have been considered in the Cochrane Review for all included studies. Hopefully, in future, a consensus will be reached concerning how to calculate effect sizes in randomized trials. For the present, it is recommended that effect sizes are presented but the definitions in the CONSORT statement, e.g., for continuous outcome "difference in means," need to be clarified to ensure that the calculation is made in the same way in all studies.

Place, publisher, year, edition, pages
2007. Vol. 55, no 8, p. 1315-1316
National Category
Physiotherapy
Research subject
Physiotherapy
Identifiers
URN: urn:nbn:se:ltu:diva-11008DOI: 10.1111/j.1532-5415.2007.01266.xISI: 000248544400033Scopus ID: 2-s2.0-34547125557Local ID: 9e6f0fc0-66d8-11dc-a0c3-000ea68e967bOAI: oai:DiVA.org:ltu-11008DiVA, id: diva2:983957
Note
Godkänd; 2007; 20070919 (eriros)Available from: 2016-09-29 Created: 2016-09-29 Last updated: 2018-07-10Bibliographically approved

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Rosendahl, Erik

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