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Carbohydrate conjugation through microwave-assisted functionalization of single-walled carbon nanotubes using perfluorophenyl azides
Royal Institute of Technology, Department of Chemistry.
Royal Institute of Technology, Department of Chemistry.ORCID iD: 0000-0001-7469-4197
Department of Chemistry, University of Massachusetts, Lowell.
Organic Chemistry, School of Chemical Science and Engineering, KTH – Royal Institute of Technology, Stockholm, Royal Institute of Technology, Department of Chemistry.
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2015 (English)In: Carbohydrate Research, ISSN 0008-6215, E-ISSN 1873-426X, Vol. 405, p. 33-38Article in journal (Refereed) Published
Abstract [en]

Carbohydrate-functionalized single-walled carbon nanotubes (SWNTs) were synthesized using microwave-assisted reaction of perfluorophenyl azide with the nanotubes. The results showed that microwave radiation provides a rapid and effective means to covalently attach carbohydrates to SWNTs, producing carbohydrate-SWNT conjugates for biorecognition. The carbohydrate-functionalized SWNTs were furthermore shown to interact specifically with cognate carbohydrate-specific proteins (lectins), resulting in predicted recognition patterns. The carbohydrate-presenting SWNTs constitute a new platform for sensitive protein-or cell recognition, which pave the way for glycoconjugated carbon nanomaterials in biorecognition applications.

Place, publisher, year, edition, pages
2015. Vol. 405, p. 33-38
National Category
Physical Chemistry
Research subject
Chemistry of Interfaces
Identifiers
URN: urn:nbn:se:ltu:diva-11360DOI: 10.1016/j.carres.2014.09.006Local ID: a4ea1338-b486-4646-aeb3-10a5dead1505OAI: oai:DiVA.org:ltu-11360DiVA, id: diva2:984310
Note
Upprättat; 2016; 20160413 (inah)Available from: 2016-09-29 Created: 2016-09-29 Last updated: 2017-11-24Bibliographically approved

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Shimpi, Manishkumar

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