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  • 51.
    Jalkanen, Ville
    et al.
    Umeå University. Department of Applied Physics and Electronics.
    Andersson, Britt M.
    Umeå University. Department of Applied Physics and Electronics.
    Bergh, Anders
    Umeå University, Department of Medical Biosciences, Pathology.
    Ljungberg, Börje
    Umeå University, Department of Surgical and Perioperative Science, Urology and Andrology.
    Lindahl, Olof
    Detection of prostate cancer with a resonance sensor2005In: Proceedings of the XIIIth Nordic Baltic Conference on Biomedical Engineering and Medical Physics: NBC'05, IFMBE , 2005, p. 130-131Conference paper (Other academic)
  • 52.
    Jalkanen, Ville
    et al.
    Umeå University. Department of Applied Physics and Electronics.
    Andersson, Britt M.
    Umeå University. Department of Applied Physics and Electronics.
    Bergh, Anders
    Umeå University, Department of Medical Biosciences, Pathology.
    Ljungberg, Börje
    Umeå University, Department of Surgical and Perioperative Science, Urology and Andrology.
    Lindahl, Olof
    Prostate tissue stiffness as measured with a resonance sensor system: a study on silicone and human prostate tissue in vitro2006In: Medical and Biological Engineering and Computing, ISSN 0140-0118, E-ISSN 1741-0444, Vol. 44, no 7, p. 593-603Article in journal (Refereed)
    Abstract [en]

    Prostate cancer is the most common form of cancer in men in Europe and in the USA. Some prostate tumours are stiffer than the surrounding normal tissue, and it could therefore be of interest to measure prostate tissue stiffness. Resonance sensor technology based on piezoelectric resonance detects variations in tissue stiffness due to a change in the resonance frequency. An impression-controlled resonance sensor system was used to detect stiffness in silicone rubber and in human prostate tissue in vitro using two parameters, both combinations of frequency change and force. Variations in silicone rubber stiffness due to the mixing ratio of the two components could be detected (p<0.05) using both parameters. Measurements on prostate tissue showed that there existed a statistically significant (MANOVA test, p<0.001) reproducible difference between tumour tissue (n=13) and normal healthy tissue (n=98) when studying a multivariate parameter set. Both the tumour tissue and normal tissue groups had variations within them, which were assumed to be related to differences in tissue composition. Other sources of error could be uneven surfaces and different levels of dehydration for the prostates. Our results indicated that the resonance sensor could be used to detect stiffness variations in silicone and in human prostate tissue in vitro. This is promising for the development of a future diagnostic tool for prostate cancer

  • 53.
    Jalkanen, Ville
    et al.
    Umeå University. Department of Applied Physics and Electronics.
    Andersson, Britt M.
    Umeå University. Department of Applied Physics and Electronics.
    Bergh, Anders
    Umeå University, Department of Medical Biosciences, Pathology.
    Ljungberg, Börje
    Department of Surgical and Preoperative Science, Urology and Andrology, Umeå University.
    Lindahl, Olof
    Resonance sensor for prostate tissue stiffness measurement: detecting prostate cancer2006In: World Congress on Medical Physics and Biomedical Engineering: August 27 - September 1, 2006, Seoul, IFMBE , 2006Conference paper (Other academic)
  • 54.
    Jalkanen, Ville
    et al.
    Umeå University. Department of Applied Physics and Electronics.
    Andersson, Britt M.
    Umeå University. Department of Applied Physics and Electronics.
    Bergh, Anders
    Umeå University, Department of Medical Biosciences, Pathology.
    Ljungberg, Börje
    Umeå University, Department of Surgical and Perioperative Science, Urology and Andrology.
    Lindahl, Olof
    Resonance sensor measurements of stiffness variations in prostate tissue in vitro: a weighted tissue proportion model2006In: Physiological Measurement, ISSN 0967-3334, E-ISSN 1361-6579, Vol. 27, no 12, p. 1373-86Article in journal (Refereed)
    Abstract [en]

    Prostate cancer is the most common type of cancer in men in Europe and the US. The methods to detect prostate cancer are still precarious and new techniques are needed. A piezoelectric transducer element in a feedback system is set to vibrate with its resonance frequency. When the sensor element contacts an object a change in the resonance frequency is observed, and this feature has been utilized in sensor systems to describe physical properties of different objects. For medical applications it has been used to measure stiffness variations due to various patho-physiological conditions. In this study the sensor's ability to measure the stiffness of prostate tissue, from two excised prostatectomy specimens in vitro, was analysed. The specimens were also subjected to morphometric measurements, and the sensor parameter was compared with the morphology of the tissue with linear regression. In the probe impression interval 0.5-1.7 mm, the maximum R(2) > or = 0.60 (p < 0.05, n = 75). An increase in the proportion of prostate stones (corpora amylacea), stroma, or cancer in relation to healthy glandular tissue increased the measured stiffness. Cancer and stroma had the greatest effect on the measured stiffness. The deeper the sensor was pressed, the greater, i.e., deeper, volume it sensed. Tissue sections deeper in the tissue were assigned a lower mathematical weighting than sections closer to the sensor probe. It is concluded that cancer increases the measured stiffness as compared with healthy glandular tissue, but areas with predominantly stroma or many stones could be more difficult to differ from cancer

  • 55.
    Jalkanen, Ville
    et al.
    Umeå University. Department of Applied Physics and Electronics.
    Andersson, Britt M.
    Umeå University. Department of Applied Physics and Electronics.
    Lindahl, Olof
    A resonance sensor technique to detect cancer in protate: model experiments in sillicone2002In: Proceedings of the XIIth nordic-baltic conference on biomedical engineering and medical physics: June 18-22 2002, Reykjavik, Iceland, 2002, p. 33-Conference paper (Other academic)
  • 56.
    Jalkanen, Ville
    et al.
    Umeå University. Department of Applied Physics and Electronics.
    Eklund, Anders
    Umeå University Hospital, Department of Biomedical Engineering & Informatics.
    Lindahl, Olof
    Force and frequency shift from a resonance sensor for detectin of prostate cancer2004In: World Congress on Medical Physics and Biomedical Engineering: Sydney 24-29 August 2003, 2004Conference paper (Other academic)
  • 57.
    Jalkanen, Ville
    et al.
    Umeå University. Department of Applied Physics and Electronics.
    Eklund, Anders
    Umeå University Hospital, Department of Biomedical Engineering.
    Lindahl, Olof
    Utvärdering av ny parameter för detektering av prostatacancer med resonanssensor2003In: Program & sammanfattningar: Svenska Läkaresällskapets riksstämma, n [60], p Stockholmsmässan, Älvsjö, 26-28 november 2003, Stockholm: Svenska läkaresällskapet , 2003, p. 242-Conference paper (Other academic)
  • 58.
    Jalkanen, Ville
    et al.
    Umeå universitet.
    Lindahl, Olof
    Luleå University of Technology, Department of Computer Science, Electrical and Space Engineering, Signals and Systems.
    Hand-held resonance sensor instrument for soft tissue stiffness measurements: a first study on biological tissue in vitro2010In: XIIth Mediterranean Conference on Medical and Biological Engineering and Computing 2010: [MEDICON 2010] ; May 27 - 30, 2010, Chalkidiki, Greece / [ed] Panagiotis D. Bamidis; Nicolas Pallikarakis, Berlin: Springer Science+Business Media B.V., 2010, p. 463-466Conference paper (Refereed)
    Abstract [en]

    A stiffness sensitive sensor capable of measuring the stiffness of a soft object through contact has been implemented through the resonance sensor technique. This technique is based on a piezoelectric element in a feedback circuit configuration. At contact with a soft tissue the resonance frequency changes and together with force measurement it is possible to estimate the elastic stiffness of the measured object. Earlier sensor implementations have been limited to controlled indentation setups. Recently, the hand-held resonance sensor concept was introduced and evaluated on a soft tissue phantom. The aim of this study was to investigate the concept on soft biological tissue, specifically to investigate if the measured stiffness was impression speed independent. Measurements were conducted on porcine muscle tissue and a stiffness parameter and an impression speed parameter were calculated. Correlation analysis showed weak non-significant correlation suggesting that the stiffness was independent of impression speed. This was promising for further studies with the handheld resonance sensor on soft biological tissue.

  • 59.
    Jansson, Ulf
    et al.
    Institutet för tillämpad fysik och elektronik, Umeå universitet.
    Lindahl, Olof
    Luleå University of Technology, Department of Engineering Sciences and Mathematics, Fluid and Experimental Mechanics.
    Andersson, Britt M.
    Institutet för tillämpad fysik och elektronik, Umeå universitet.
    Modeling the High-Frequency Complex Modulus of a Silicone Rubber Using Standing Lamb waves and an Inverse FEM Method2014In: IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control, ISSN 0885-3010, E-ISSN 1525-8955, Vol. 61, no 12, p. 2106-2120Article in journal (Refereed)
    Abstract [en]

    To gain an understanding of the high-frequency elastic properties of silicone rubber, a finite element model of a cylindrical piezoelectric element, in contact with a silicone rubber disk, was constructed. The frequency-dependent elastic modulus of the silicone rubber was modeled by a fourparameter fractional derivative viscoelastic model in the 100 to 250 kHz frequency range. The calculations were carried out in the range of the first radial resonance frequency of the sensor. At the resonance, the hyperelastic effect of the silicone rubber was modeled by a hyperelastic compensating function. The calculated response was matched to the measured response by using the transitional peaks in the impedance spectrum that originates from the switching of standing Lamb wave modes in the silicone rubber. To validate the results, the impedance responses of three 5-mm-thick silicone rubber disks, with different radial lengths, were measured. The calculated and measured transitional frequencies have been compared in detail. The comparison showed very good agreement, with average relative differences of 0.7%, 0.6%, and 0.7% for the silicone rubber samples with radial lengths of 38.0, 21.4, and 11.0 mm, respectively. The average complex elastic moduli of the samples were (0.97 + 0.009i) GPa at 100 kHz and (0.97 + 0.005i) GPa at 250 kHz.

  • 60.
    Li, Haibo
    et al.
    Umeå University, Digital Media Lab.
    Lindahl, Olof
    Umeå universitet.
    Yao, Zhengrong
    Umeå University, Digital Media Lab.
    System för guidning av en rörlig bärarePatent (Other (popular science, discussion, etc.))
  • 61. Lindahl, Olof
    Aktivitet: Sensorer och fysiologiska mätvariabler: vad är på gång?2005Conference paper (Other (popular science, discussion, etc.))
  • 62. Lindahl, Olof
    Aktivitet: Ödemmätning med inpressionsteknik1991Conference paper (Other (popular science, discussion, etc.))
  • 63.
    Lindahl, Olof
    Luleå University of Technology, Department of Computer Science, Electrical and Space Engineering, Signals and Systems.
    Ansiktsuttryckens värld öppnas för blinda2007In: Medtech info., ISSN 1404-9759, p. 16-17Article in journal (Other (popular science, discussion, etc.))
  • 64.
    Lindahl, Olof
    Luleå University of Technology, Department of Computer Science, Electrical and Space Engineering, Signals and Systems.
    Business development of biomedical engineering inventions2006In: Proceedings of the 13th Nordic-Baltic Conference of BioMedical Engineering and Medical Physics: NBC'05, IFMBE , 2006, p. 15-16Conference paper (Other academic)
  • 65. Lindahl, Olof
    Collaboration in marketing new inventions at Umeå1990In: Clinical Engineering Update, no 7, p. 4-Article in journal (Other academic)
  • 66.
    Lindahl, Olof
    Luleå University of Technology, Department of Computer Science, Electrical and Space Engineering, Signals and Systems.
    Commercialisation of biomedical innovations2006In: World Congress on Medical Physics and Biomedical Engineering: August 27 - September 1, 2006 Seoul, Verlag Otto Lembeck, 2006Conference paper (Other academic)
  • 67. Lindahl, Olof
    Erfarenheter av utvärdering av Marie Curie ansökning inom Life Science2003In: Program & sammanfattningar: Svenska Läkaresällskapets riksstämma, n [60], p Stockholmsmässan, Älvsjö, 26-28 november 2003, Stockholm: Svenska läkaresällskapet , 2003, p. 243-Conference paper (Other academic)
  • 68. Lindahl, Olof
    Experiences from refinements of medical and technical research results at Umeå university into commercial products for the health care market1996In: Proceedings of the 10th Nordic-Baltic conference on biomedical engineering.: June 9-13, Tampere, Finland 1996, 1996, p. 47-Conference paper (Other academic)
  • 69.
    Lindahl, Olof
    Luleå University of Technology, Department of Computer Science, Electrical and Space Engineering, Signals and Systems.
    From biomedical research to viable products on the health care market: a north Sweden model called CMTF2009In: World Congress on Medical Physics and Biomedical Engineering: September 7 - 12, 2009, Munich, Germany / [ed] Olaf Dössel; Wolfgang C. Schlegel, Berlin: Springer Science+Business Media B.V., 2009, p. 127-130Conference paper (Refereed)
    Abstract [en]

    A centre for research in Biomedical engineering and physics (CMTF) has been built up in Northern Sweden. The CMTF has resulted in increased growth of the biomedical engineering activities both in academia and in the industry in Northern Sweden. Fore example six new companies have resulted from the research. Cooperation was built up between the CMTF and 15 established companies. A research company for business development of the research results from the centre has been established and is owned by the project managers in the centre. The company is called CMTF Business Development Co Ltd and it has also increased the interest for business development questions among the scientists in the centre, i.e. encouraged entrepreneurship

  • 70.
    Lindahl, Olof
    Luleå University of Technology, Department of Computer Science, Electrical and Space Engineering, Signals and Systems.
    Från forskningsidé till kommersiell produkt på hälso- och sjukvårdsmarknaden2009In: Högskolor och samhälle i samverkan, HSS09, 2009, p. 67-68Conference paper (Other academic)
    Abstract [sv]

    SyfteI detta föredrag redogörs för hur vi i norra Sverige arbetar med processen att skapa affärer utifrån medicintekniska forskningsresultat. I allmänhet betraktas denna process oavsett branschområde som mycket svår. Föredraget belyser hur vi genom samverkan med de regionala innovationssystemen samt med företag och med hälso-och sjukvården framför allt i Västeroch Norrbotten lyckats skapa en modell för affärsutveckling av forskningsresultat i vår bransch. Medicinteknisk forskning är av stort intresse för medicinteknisk industri. Storleksordningen 20 miljarder kronor utgör omsättningen per år för medicintekniska produkter och tjänster i Sverige. Processer för att kommersialisera medicintekniska forskningsinnovationer är viktiga för att vidmakthålla och utveckla Sverige som framstående medicinteknisk nation. Vi har därför bildat ett centrum (CMTF) för medicinsk teknik som innefattar de medicintekniska forskningsverksamheterna i Umeå och Luleå- idag 17 delprojekt.MetodCMTF har samverkat med de befintliga innovationssystemen i Umeå och Luleå för att utveckla en branschspecifik affärsutvecklingsmodell. Genom samarbete med företag i branschen och tillsammans med lokala och nationella finansiärer arbetar vi med att kommersialisera gångbara produktidéer från centrets forskning. Hittills har sex nya företag startats, 9 patent tagits och ett stort antal workshops genomförts i samverkan med industrin. På senare tid har vi paketerat affärsmodellen i ett forskarägt utvecklingsföretag CMTF Affärsutveckling AB som är en plantskola för de nya produktidéerna. I affärsutvecklingsprocessen har vi framförallt arbetat med patentering som hjälpmedel för att utreda nyhetsvärdet hos innovationerna. Därefter har marknaden för innovationen undersökts. Om resultaten har varit positiva så har vi gått vidare med de olika steg som behövts för att åstadkomma en fullständig affärsplan. Affärsplanen har slutligen använts som beslutsunderlag för finansiering och bolagsbildning.ResultatHittills har vi kunnat konstatera att kommersialisering av forskningsresultat är svårt och kräver mycket tid, vanligen många år. Samtidigt ställer riskfinansiärerna kraven på kort "time to market". Vidare måste man omge sig med ett team av kompetenser (ekonomi, juridik, patenträtt mm.) för att lyckas. Ingen person har alla dessa kompetenser själv. Inom medicinsk teknik är dessutom de regulatoriska frågorna omfattande. Finns dock tålamod och driv-/entreprenörskraft så kan resultaten bli mycket lyckade. I föredraget redovisas ett exempel på hur ett forskningsresultat från CMTF utvecklats till en kommersiell produkt i företaget Bioresonator AB - en process som tagit åtta år. CMTF har idag ca 150 forskare och övrig personal som arbetar i delprojekten och centret är en av landets största forskande universitetsorganisationer inom medicinsk teknik och fysik.

  • 71.
    Lindahl, Olof
    Umeå universitet.
    Förfarande och anordning vid mätning av ödemPatent (Other (popular science, discussion, etc.))
    Abstract [en]

    The present invention concerns a method and a device for measurement and assessment of oedema, especially with regard to a combination of the two types of oedema called pitting oedema and brawny oedema. The method comprises the steps of reading the frequency of a freely and in resonance oscillating sensor, the application of the in resonance oscillating sensor against an oedema to a certain depth of depression and the continuous reading of the force of application and the resonance frequency of the in resonance oscillating sensor. The device comprises a measuring head that is adjustably supported by a stand and exhibits partly a freely and in resonance oscillating sensor (6) for making a resonance system together with the oedema when applied to it, partly a means of reading the current resonance frequency of the sensor, partly means (5) for measuring the force with which the sensor is applied to the oedema. Information is hereby obtained concerning the degree of stiffness as a measure of brawny oedema through read frequency shift and the degree of displaced fluid obtained as a measure of pitting oedema through measurement of decay of force

  • 72. Lindahl, Olof
    Medicinsk teknik i Umeå utvecklas i samarbete mellan Unikum vid universitetet och medicintekniska avdelningen vid regionsjukhuset1989In: Sjukhuset, ISSN 0346-1130, Vol. 66, p. 494-495Article in journal (Other academic)
  • 73. Lindahl, Olof
    Resonance sensors for better health care2005In: Proceedings of the 13th Nordic-Baltic Conference of BioMedical Engineering and Medical Physics: NBC 2005, IFMBE , 2005, p. 127-Conference paper (Other academic)
  • 74. Lindahl, Olof
    Teknikens roll för ekonomik kvalitet och säkerhet1992In: Medicinsk ekonomi + teknik, ISSN 1102-8068, Vol. 1, no 3, p. 56-Article in journal (Other academic)
  • 75. Lindahl, Olof
    The evaluation of a biexponential model for description of intercompartmental fluid shifts in compressed oedematous tissue1995In: Physiological Measurement, ISSN 0967-3334, E-ISSN 1361-6579, Vol. 16, no 1, p. 17-28Article in journal (Refereed)
    Abstract [en]

    A parametric model was fitted to force curve data gained by a non-invasive impression method that measures force and fluid translocation during mechanical compression of the skin. The ability of the model parameters to estimate high- and low-viscosity fluid flow in compressed areas were evaluated in a silicone rubber model and in six patients with chronic pitting oedema. Different softnesses of silicone rubber gave significantly different parameter values. The flow properties of the silicone model could be analysed in detail with the suggested model. Parameter analysis showed a higher fraction of low-viscosity fluid for oedema than for reference sites. The model parameters could be interpreted in softness value according to an international standard for consistency (ISO 2137). The suggested parametric model gave reliable and detailed information about high- and low-viscosity fluid flow and can be used to estimate intercompartmental fluid shifts in oedematous tissue

  • 76. Lindahl, Olof
    The impression technique for assessment of tissue oedema: instrumentation, evaluation and applications1993Doctoral thesis, comprehensive summary (Other academic)
  • 77. Lindahl, Olof
    et al.
    Andersson, B.
    Umeå universitet.
    Lundström, R.
    Umeå universitet.
    Ramser, Kerstin
    Luleå University of Technology, Department of Computer Science, Electrical and Space Engineering, Signals and Systems.
    From biomedical research to spin-off companies for the health care market2010In: XIIth Mediterranean Conference on Medical and Biological Engineering and Computing 2010: [MEDICON 2010] ; May 27 - 30, 2010, Chalkidiki, Greece / [ed] Panagiotis D. Bamidis; Nicolas Pallikarakis, Berlin: Springer Science+Business Media B.V., 2010, p. 624-626Conference paper (Refereed)
    Abstract [en]

    Through research at the centre for biomedical engineering and physics (CMTF) seven new companies have been established in Northern Sweden. The activities have generated growth both in academia at the universities and in the industry in Northern Sweden. Cooperation was built up between the 23 research projects and more than 20 established companies in the field of biomedical engineering. A researcher-owned company for business development of the research results from the CMTF has been established, CMTF Business Development Co Ltd, and has launched its first spin-off company in the autumn 2009. It has also increased the interest for commercial and entrepreneurship questions among the scientists in the centre. So far seven spin-off companies have resulted from the CMTF-research.

  • 78.
    Lindahl, Olof
    et al.
    Luleå University of Technology, Department of Computer Science, Electrical and Space Engineering, Signals and Systems.
    Andersson, B.M.
    Centre for Biomedical Engineering and Physics, Umeå University.
    Lundström, R.
    Centre for Biomedical Engineering and Physics, Umeå University.
    Ramser, Kerstin
    Luleå University of Technology, Department of Computer Science, Electrical and Space Engineering, Signals and Systems.
    Biomedical engineering research improves the health care industry2013In: XIII Mediterranean conference on medical and biological engineering and computing: MEDICON 2013, 25-28 September 2013, Seville, Spain / [ed] Laura M. Roa Romero, Wien: Encyclopedia of Global Archaeology/Springer Verlag, 2013, Vol. VIII, p. 1124-1126Conference paper (Refereed)
    Abstract [en]

    The health care industry is dependent on new innovations for its survival and expansion. Health care innovations are also important for improving patient care. Through activities at the centre for biomedical engineering and physics (CMTF) we have generated growth both in academia at the universities and in the industry in northern Sweden. Fruitful cooperation was generated between 26 research projects and about 15 established companies in the field of biomedical engineering. The established researcher-owned company for business development of the research results from the CMTF, CMTF Business Development Co Ltd, has so far launched three spin-off companies and has 10 new business leads to develop. The activities have also increased the interest for commercialization and entrepreneurship among the scientists in the centre. So far a total of nine spin-off companies have resulted from the CMTF-research since the year 2000 that has improved the health care market in northern Sweden

  • 79.
    Lindahl, Olof
    et al.
    Luleå University of Technology, Department of Computer Science, Electrical and Space Engineering, Signals and Systems.
    Andersson, Britt
    Institutet för tillämpad fysik och elektronik, Umeå universitet.
    Karlsson, Stefan
    Medicinsk teknik, NUS, Umeå.
    Lundström, Ronnie
    Medicinsk teknik, NUS, Umeå.
    Ramser, Kerstin
    Från forskningsidé till kommersiell produkt på marknaden: CMTF, ett framgångsexempel2009Conference paper (Other academic)
  • 80.
    Lindahl, Olof
    et al.
    Luleå University of Technology, Department of Computer Science, Electrical and Space Engineering, Signals and Systems.
    Andersson, Britt
    Centre for Biomedical Engineering and Physics, Umeå University.
    Lundström, Ronnie
    Centre for Biomedical Engineering and Physics, Umeå University.
    Hallberg, Josef
    Luleå University of Technology, Department of Computer Science, Electrical and Space Engineering, Signals and Systems.
    Development of spin-off companies for health care from biomedical research results2011Conference paper (Refereed)
  • 81.
    Lindahl, Olof
    et al.
    Luleå University of Technology, Department of Computer Science, Electrical and Space Engineering, Signals and Systems.
    Andersson, Britt M.
    Centre for Biomedical Engineering and Physics, Umeå University.
    Lundström, Ronnie J.I.
    Centre for Biomedical Engineering and Physics, Umeå University.
    Hallberg, Josef
    Luleå University of Technology, Department of Computer Science, Electrical and Space Engineering, Computer Science.
    A triple-helix model for refining biomedical engineering research into spin-off companies for the health care market2012In: World Congress on Medical Physics and Biological Engineering, May 26-31, 2012, Beijing, China / [ed] Mian Long, Berlin: Encyclopedia of Global Archaeology/Springer Verlag, 2012, p. 2088-2090Conference paper (Refereed)
    Abstract [en]

    Triple-Helix activities at the centre for biomedical engineering and physics (CMTF) have generated growth both in academia at the universities and in the industry in Northern Sweden. Cooperation was built up between the 26 research projects and about 15 established companies in the field of biomedical engineering. The established researcher - owned company for business development of the research results from the CMTF, CMTF Business Development Co Ltd, has so far launched one spin-off company and has 15 new business leads to business develop. The activities have also increased the interest for commercial and entrepreneurship questions among the scientists in the centre. So far a total of seven spin-off companies have resulted from the CMTF-research since the year 2000

  • 82. Lindahl, Olof
    et al.
    Bergh, Anders
    Umeå University Hospital, Department of Biomedical Engineering.
    Damber, Jan-Erik
    Umeå University Hospital, Department of Physiology.
    Ängquist, Karl-Axel
    Umeå University Hospital, Department of Surgery.
    Evaluation of an impression technique for assessment of subcutaneous oedema in man with a rat testis model1993In: World Congress on Medical Physics and Biomedical Engineering: held in Kyoto on 7-12 July 1991, 1993Conference paper (Other academic)
  • 83. Lindahl, Olof
    et al.
    Bergh, Anders
    Umeå University, Department of Physiology.
    Damber, Jan-Erik
    Umeå University, Department of Physiology.
    Ängquist, Karl-Axel
    Umeå University, Department of Physiology.
    Evaluation of the impression technique by measuring interstitial oedema in rat testis1991In: Acta Physiologica Scandinavica, ISSN 0001-6772, E-ISSN 1365-201X, Vol. 143, no 3, p. 255-60Article in journal (Refereed)
    Abstract [en]

    The impression method for assessment of subcutaneous oedema was evaluated in a rat testis model where the testicular interstitial fluid volume was changed both artificially by infusion of rat plasma and pharmacologically by administration of human chorionic gonadotrophin. Both the integral value and the impression force value, as measured with the impression method, changed with infused volume, and changes as small as 16 microliters (approximately 7% of the total interstitial fluid volume in a testis) could be detected. Rats were treated with a single injection of 100 i.u. human chorionic gonadotrophin in order to induce changes in the volume of interstitial fluid in the testis. Both the integral value and the impression force value seemed to reveal information on testicular interstitial fluid volume in rats treated with human chorionic gonadotrophin that was similar to data revealed by measuring the actual fluid content in the testis. Interstitial fluid volume measured morphometrically in the contralateral testis in human chorionic gonadotrophin-treated rats was significantly correlated to the impression force value (r = 0.75) and the integral value (r = 0.52). This rat testis model proved to be an interesting experimental set-up for evaluation of the impression technique.

  • 84. Lindahl, Olof
    et al.
    Bergh, Anders
    Umeå University, Department of Physiology.
    Damber, Jan-Erik
    Umeå University, Department of Physiology.
    Ängquist, Karl-Axel
    Umeå University, Department of Physiology.
    Rat testis oedema measured with the impression technique: effects of hyaluronan, albumin, rat plasma and saline1994In: Medical and Biological Engineering and Computing, ISSN 0140-0118, E-ISSN 1741-0444, Vol. 32, no 3, p. 350-4Article in journal (Refereed)
  • 85. Lindahl, Olof
    et al.
    Bäcklund, Tomas
    Umeå University, Department of Biomedical Engineering.
    Chrisianson, sven-Åke
    Umeå university.
    Nilsson, Lars-Göran
    Umeå university.
    Silfvenius, Herbert
    Umeå University Hospital, Department of Neurosurgery.
    Utrustning för testning av hemisfärminne med visuell halvfältsteknik1984In: Program & sammanfattningar. 41: Älvsjö Stockholm 28-30 nov 1984, Stockholm: Svenska läkaresällskapet , 1984, p. 207-Conference paper (Other academic)
  • 86. Lindahl, Olof
    et al.
    Bäcklund, Tomas
    Umeå University, Department of Biomedical Engineering.
    christianson, Sven-Åke
    Umeå university.
    Nilsson, Lars-Göran
    Umeå university.
    Silfvenius, Herbert
    Umeå University Hospital, Department of Neurosurgery.
    An improved optical eye movement detector for visual half-field studies of cerebral hemisphere memory1988In: Journal of Medical Engineering & Technology, ISSN 0309-1902, E-ISSN 1464-522X, Vol. 12, no 3, p. 106-11Article in journal (Refereed)
    Abstract [en]

    106-11AB - An instrument for the evaluation of cerebral hemisphere memory using the visual half-field (VHF) technique is described. The object was to improve the existing VHF-techniques by means of an infra-red eye movement detector to control visual fixation, and to automatically control the presentation of visual stimuli. The instrument consists of four functional parts; visual presentation; optical eye movement control; electronic programming; and reaction time measuring. The instrument has been used on normal controls and in neuropsychological pre- and post-operative investigations on patients with drug resistant partial epilepsy. It has proved easy to use and reveals valuable information about hemisphere memory function. The use of an optical eye movement detector together with electronic logic has improved the accuracy and reliability of the VHF-test. A schematic outline of the instrument and a brief description of electronic circuitry are given.

  • 87. Lindahl, Olof
    et al.
    Bäcklund, Tomas
    Umeå University Hospital, Department of Biomedical Engineering.
    Karlsson, S.
    Umeå universitetssjukhus.
    Söderberg, T.
    Umeå universitetssjukhus.
    HASTRAS: en persondatorbaserad kraftmätare för analys av handens och fingrarnas motoriska förmåga1988In: Program & sammanfattningar. 45: Älvsjö, Stockholm 29 nov. - 2 dec. 1988, Stockholm: Svenska läkaresällskapet , 1988, p. 237-Conference paper (Other academic)
  • 88. Lindahl, Olof
    et al.
    Bäcklund, Tomas
    Umeå University Hospital, Department of Biomedical Engineering.
    Karlsson, S.
    Umeå universitetssjukhus.
    Söderberg, T.
    Umeå universitetssjukhus.
    PC-based equipment for the assessment of strength during various hand grips1988In: Physics in Medicine and Biology, ISSN 0031-9155, E-ISSN 1361-6560, Vol. 33, no Suppl. 1, p. 277-Article in journal (Refereed)
  • 89. Lindahl, Olof
    et al.
    Bäcklund, Tomas
    Umeå University Hospital, Department of Biomedical Engineering.
    Lundström, B.
    Sjödin, Jan-Gunnar
    Umeå University Hospital, Department of Urology and Andrology.
    Utrustning för långtidsregistrering av njurbäckentryck vid hydronefros1985In: Program & sammanfattningar. 42: Älvsjö, Stockholm, 27-29 nov. 1985, Stockholm: Svenska läkaresällskapet , 1985, p. 209-Conference paper (Other academic)
  • 90. Lindahl, Olof
    et al.
    Bäcklund, Tomas
    Umeå University Hospital, Department of Biomedical Engineering.
    Sjödin, Jan-Gunnar
    Umeå University Hospital, Department of Urology and Andrology.
    Monitoring of renal pelvic pressure in patients with hydronephrosis1995In: Physiological Measurement, ISSN 0967-3334, E-ISSN 1361-6579, Vol. 16, no 3, p. 169-79Article in journal (Refereed)
    Abstract [en]

    A diagnostic method for the determination of obstructions in the pelvoureteral junction in patients with suspected idiopathic hydronephrosis is described and discussed. Two microtransducer catheters (MTCs) with infusion lumens are inserted under fluoroscopic control, one into the renal pelvis and the other in the perirenal space as a reference. The pressure values obtained are stored on a portable microcomputer system, carried by the ambulatory patients. Renal pelvic pressure, intra-abdominal pressure and differential pressure are calculated and displayed as time-pressure diagrams on a plotter. The pressures can be measured for long periods (3-24 h). Furthermore, steady state conditions can be evaluated during pelvic infusion of saline. The results from the pressure measurements are compared with clinical and radiological evaluations. Our results show that this method of long-term monitoring of intrapelvic pressure together with intra-abdominal pressure contributes to the evaluation of patients with suspected pelvoureteral obstructions and complements other methods in the preoperative investigation. However, this study reveals difficulties with measurements of intra-abdominal pressure. Carrying the equipment was not inconvenient for the patients

  • 91. Lindahl, Olof
    et al.
    Bäcklund, Tomas
    Umeå University Hospital, Department of Biomedical Engineering.
    Sjödin, Jan-Gunnar
    Umeå University Hospital, Department of Urology and Andrology.
    Bjerle, Per
    Umeå University, Department of Clinical Physiology.
    Lundström, B.
    Method for the assessment of renal pelvic pressures in patients with hydornephrosis1987In: Proceedings of the VIIth Nordic meeting on medical and biological engineering / [ed] Hroar Piene; sigmund Kvernes, Institute of biomedical engineering, Faculty of medicine, Univ. of Trondheim , 1987, p. B15-Conference paper (Other academic)
  • 92.
    Lindahl, Olof
    et al.
    Luleå University of Technology, Department of Computer Science, Electrical and Space Engineering, Signals and Systems.
    Constantinou, Christos
    Department of Urology, Stanford University School of Medicine.
    Eklund, Anders
    Biomedical Engineering and Informatics, Umeå University Hospital.
    Murayama, Yoshinobu
    College of Engineering, Nihon University.
    Hallberg, Per
    Biomedical Engineering and Informatics, Umeå University Hospital.
    Omata, Sadao
    College of Engineering, Nihon University.
    Tactile resonance sensors in medicine2009In: Journal of Medical Engineering & Technology, ISSN 0309-1902, E-ISSN 1464-522X, Vol. 33, no 4, p. 263-273Article in journal (Refereed)
    Abstract [en]

    Tactile sensors in general are used for measuring the physical parameters associated with contact between sensor and object. Tactile resonance sensors in particular are based on the principle of measuring the frequency shift, Δf, defined as the difference between a freely vibrating sensor resonance frequency and the resonance frequency measured when the sensor makes contact to an object. Δf is therefore related to the acoustic impedance of the object and can be used to characterize its material properties. In medicine, tactile resonance sensor systems have been developed for the detection of cancer, human ovum fertility, eye pressure and oedema. In 1992 a Japanese research group published a paper presenting a unique phase shift circuit to facilitate resonance measurements. In this review we summarize the current state-of-the-art of tactile resonance sensors in medicine based on the phase shift circuit and discuss the relevance of the measured parameters for clinical diagnosis. Future trends and applications enabled by this technology are also predicted.

  • 93. Lindahl, Olof
    et al.
    Eklund, Anders
    Umeå University Hospital, Department of Biomedical Engineering & Informatics.
    Ny ögontrycksmätare baserad på resonanssensorteknologi2000In: NUTEKs medicintekniska konferens, Linköping 2000, NUTEK , 2000Conference paper (Other academic)
  • 94. Lindahl, Olof
    et al.
    Eklund, Anders
    Umeå University Hospital, Department of Biomedical Engineering & Informatics.
    Resonanssensorteknik för medicinsk diagnostik1999In: NUTEKs medicintekniska konferens 1999, NUTEK , 1999Conference paper (Other academic)
  • 95. Lindahl, Olof
    et al.
    Eklund, Anders
    Umeå University Hospital, Department of Biomedical Engineering & Informatics.
    Vibrationssensor för värdering av vävnadshårdhet1998In: NUTEKs medicintekniska konferens 1998, NUTEK , 1998Conference paper (Other academic)
  • 96. Lindahl, Olof
    et al.
    Eklund, Anders
    Umeå University Hospital, Department of Biomedical Engineering & Informatics.
    Murayama, Yoshinobu
    Nihon University.
    Omata, Sadao
    Nihon University.
    Review of tactile resonance sensors in medicine2006In: World Congress on Medical Physics and Biomedical Engineering: August 27 - September 1, 2006, Seoul, IFMBE , 2006Conference paper (Other academic)
  • 97. Lindahl, Olof
    et al.
    Eklund, Anders
    Umeå University Hospital, Department of Biomedical Engineering.
    Omata, Sadao
    Nihon University.
    A resonator sensor for detection of elastic related properties of human skin2000In: World Congress on Medical Physics and Biomedical Engineering,: July 23-28, 2000, Chicago, USA, 2000Conference paper (Other academic)
  • 98. Lindahl, Olof
    et al.
    Eklund, Anders
    Umeå University Hospital, Department of Biomedical Engineering.
    Santala, Kenneth
    Umeå University, Department of Clinical Science, Ophthalmology.
    Lindén, Christina
    Umeå University, Department of Clinical Science, Ophthalmology.
    Koskela, Timo
    Koskela Eye Clinic, Umeå.
    Hallberg, Per
    Umeå University Hospital, Department of Biomedical Engineering & Informatics.
    Ögontrycksmätning på laserbehandlade hornhinnor2004In: Svenska läkaresällskapets riksstämma 24-26 november 2004, Stockholm: Svenska läkaresällskapet , 2004, p. F15-Conference paper (Other academic)
  • 99. Lindahl, Olof
    et al.
    Eklund, Anders
    Umeå University Hospital, Department of Biomedical Engineering.
    Ängquist, Karl-Axel
    Umeå University Hospital, Department of Surgery.
    Mätning av elastiska egenskaper hos hud med en resonsssensor2000In: Program & sammanfattningar. [57]: Svenska mässan, Göteborg, 29 november-1 december 2000, Stockholm: Svenska läkaresällskapet , 2000, p. 249-Conference paper (Other academic)
  • 100.
    Lindahl, Olof
    et al.
    Umeå universitet.
    Forchheimer, Robert
    Linköping University, Image Coding Group.
    Li, Haibo
    Umeå University, Digital Media Lab.
    System and method for interpretation of visual informationPatent (Other (popular science, discussion, etc.))
    Abstract [en]

    In a system (10) and a method for interpreting visual information and transmitting it to a human being through tactile influence of sensorial organs in its body, the system has a sensor module (12) capturing visual information; a control module (14), interpreting the captured information and controlling a tactile actuator module (16) in accordance with the interpreted information. An actuator module (16) transmits the interpreted information to a human being by electro-mechanically influencing sensorial organs in the skin of the human being, thereby creating an image in its brain. An image is corresponding to the visual information transmitted through the electro-mechanical actuator module (16).

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