The use of technology in business process is gaining much attention, and many businesses today rely on technology as an important part of an efficient and effective way of meeting customers’ satisfaction. This study deals with the adoption of a proper and electronic means of tracking counterfeit drugs in the supply chain (distribution network) through the use of RFID technology. The case of the Ghanaian pharmaceutical group KAMA is considered. The main objective consists in finding out how the adoption of RFID technology would help tracking counterfeit drugs in the supply chain of this company and which benefits this could generate. Three research questions are stated and a qualitative approach is adopted. Field observation, a series of interviews with management and field workers of Kama as well as a questionnaire allowed collecting the data. The analysis of the data showed that RFID technology should be adopted by Kama to replace the present costly and relatively inefficient way of tracking counterfeit drugs. The motivation of workers to be trained on RFID as well as the company readiness to train employees represent major factors for adoption and implementation of RFID to track counterfeit drugs and hence contribute to increase the profit margin and improve Kama’s image on the market. Recommendations are finally made on the methodology to be adopted by Kama to implement and use RFID technology to track counterfeit drugs.