People living in the coastal regions of Bangladesh suffer extremely due to floods. Every year 20% of the land mass (∼27,000 km2) and 30 million inhabitants are exposed to flooding that triggers casualties, infrastructural damage, and deprived access to basic needs. Many policies and strategies already exist for managing flood-related disasters. Flood-shelters save lives but rarely equipped with sufficient food, clean water, sanitation, and electricity. New strategies are required to provide resilience in flood prone areas. This conceptual paper presents an innovative and integrated approach for up-scaling and enhancement of resilience in the flood prone regions of Bangladesh. The paper shows a conceptual design for a floating house with six innovation techniques for self-sufficiency and durability. The techniques include wind and flood tolerant structure, vertical gardening, rainwater harvesting, poultry and bio-digester unit, cage fishing, and renewable energy implementation. The techniques are low-tech and cost-efficient. Use of locally available materials enhances the resilience before and after flood. The design presents equality, balance and immense opportunities for the inhabitants. The 3R strategy (reduce, reuse and recycle) is one of the fundamental concepts of this floating house design. The design explores the possibilities of food security, waste management and energy challenge.