Due to new environmental regulations, Pb-free engine bearing materials are becoming more common and there is a need for studying their tribological performance. Under severe and nonideal operating conditions, failure due to seizure can occur in engine bearings. In this work, seizure behaviour of different multi-layered engine bearing materials has been studied by using a block-on-ring test set up. These materials included Al-Sn based lining with no overlay, bronze lining with Polyamide-imide (PAI) based overlay containing MoS2 and graphite, bronze lining with two overlays of Al-Sn based and PAI based overlay, bronze based lining with Sn-based overlay and bismuth (Bi) containing bronze with Sn-based overlay. Tests were performed by progressively increasing the load in a stepwise manner at a constant speed under unidirectional dry sliding conditions. Bronze based lining with a PAI based overlay containing MoS2 and graphite did not exhibit seizure up to a load of 475 N. For Al-Sn based lining without overlay, seizure occurs at relatively lower load of 125 N. In most cases, there is material transfer onto the counter surface test ring. The test materials, counter surfaces and the wear debris were analysed using SEM incorporating EDS with a view to explain the seizure mechanisms.