The main issues addressed by APOLLON are the present lack of Living Lab harmonisation and collaboration, and the serious difficulties of SMEs in engaging in cross-border innovation. APOLLON will demonstrate the positive impacts of cross-border domain-specific Living Lab networks, by setting up an advanced pilot composed of 4 thematically focused European-wide Living Lab experiments. In the experiments, SMEs are enabled to take part in cross-border Living Lab experiments beyond their home markets, and are supported by large industrial companies, academic centres and other stakeholders. The APOLLON pilot aims at the sharing and harmonisation of Living Lab approaches and platforms between networks of exemplary European Living Labs, and the subsequent evaluation results and the set up of sustainable domain-specific networks on a European and global level. APOLLON addresses 4 major domains in which ICT products and services innovation may benefit most from cross-border Living Lab networking. These are: (1) Homecare and Independent Living, (2) Energy Efficiency, (3) eManufacturing and (4) eParticipation.