AMBITIOUS [1] aims at providing a fundamental technological infrastructure, which will offer advanced data aggregation and clean-up, analytics, AI-enabled forecasting and secure information exchange mechanisms, via a transparent computing continuum infrastructure, to be integrated with existing, mature services of SMEs, unleashing for them yet unforeseen functionalities and opening up new pathways of commercial exploitation. The envisaged fundamental infrastructure will be provided via the deployment of technological pillars, which will interact with existing services towards supporting the envisioned functionalities. The purpose of a pillar is to provide the same generic functionalities to diverse services, demonstrated by a various set of specific use cases, as a concrete processing chain, aiming at avoiding unnecessary redundancy of resources and budget. This paper presents the focused use cases.